Will RM43 Kill Trees? (How Fast It Works, Tree Types, Mix Ratio, and RM43 vs. Roundup)

By Palm Tree Pros Editorial Team Updated 12 min read
Gravel driveway edge with weeds killed by RM43 total vegetation control next to a mature maple tree whose roots run under the gravel

Key Takeaways

Yes, RM43 can injure or kill trees. It is a non-selective vegetation-control herbicide, not a product intended for use around desirable trees.

If your goal is to preserve a tree, the safest approach is to keep RM43 away from its foliage, trunk, and root zone.

If a tree needs to be removed, use a qualified tree-care professional and check local tree-removal rules rather than relying on herbicide.

Will RM43 Kill Trees?

Yes, RM43 can damage trees and may contribute to their death if they receive a sufficiently harmful exposure. However, it will not necessarily kill every tree it contacts.

The result depends on several factors:

University extension guidance warns that soil-active herbicides such as imazapyr can damage or kill desirable woody plants when applied inappropriately near their roots.

Can RM43 Kill a Tree Without Touching Its Leaves?

Potentially, yes. Tree roots extend beyond the trunk and often beyond the visible canopy. If roots encounter soil containing a root-active herbicide, the tree may absorb it and develop injury.

The RM43 label instructs users not to apply the product over desirable trees’ and shrubs’ root systems. Its directions include a buffer based on twice the distance from the trunk to the drip line. Follow the current label for the exact product and use site.

RM43 drip line buffer around a desirable tree The RM43 label buffer is based on twice the distance from the trunk to the drip line. Roots extend beyond the canopy, so keep RM43 outside this zone. Keep RM43 Out of the Root Zone The label buffer is based on twice the trunk to drip line distance. Drip lineDrip line 2x buffer2x buffer trunk to drip line twice that distance Never apply RM43 inside the red lines Labeledarea only
The RM43 label buffer is based on twice the trunk to drip line distance.

This is one reason RM43 should not be treated as an ordinary spot weed killer around established trees.

How Fast Will RM43 Kill Trees?

There is no reliable, universal timeline for how quickly RM43 will injure or kill a tree. It is not possible to predict an exact number of days from the product name alone.

The visible effects depend on the amount absorbed, the tree species, the exposure route, and the growing conditions.

Time after exposureWhat may happen
First few daysThere may be no obvious visible symptoms, particularly after root exposure
Following days or weeksSome trees may develop abnormal foliage, yellowing, reduced growth, or other signs of stress
Following weeks or monthsPersistent exposure or significant injury may lead to canopy thinning, branch dieback, or a decline in overall health
Longer termSeverely affected trees may die, while others may recover partially or show lingering damage

These are general possibilities, not a guaranteed RM43-specific timetable. Extension guidance on herbicide injury and tree-root damage notes that symptoms can be delayed and that the full outcome may take time to become apparent.

Why Does Tree Damage Sometimes Take So Long to Appear?

A tree has stored energy reserves and an extensive root system. It may continue producing leaves for a while even if some roots or other tissues have been injured.

Symptoms can become more obvious during hot, dry weather or when the tree is trying to produce new growth.

A tree that still looks healthy a few days after suspected exposure should not automatically be considered unaffected.

What Is RM43 Weed Killer?

RM43 Total Vegetation Control is a non-selective herbicide designed to control vegetation in specified non-crop areas, such as gravel paths, driveways, fence lines, and other locations where plant growth is unwanted.

Unlike a basic weed killer, RM43 combines two active ingredients:

Active ingredientPercentage in RM43Main function
Glyphosate isopropylamine salt43.68%Controls susceptible existing vegetation after the chemical is absorbed by the plant
Imazapyr isopropylamine salt0.78%Adds control of susceptible vegetation and residual activity in treated soil

These percentages are listed in the product registration information and manufacturer materials. The EPA’s pesticide label resources explain how to read a registered label like this one.

The second ingredient is especially important when considering trees. Imazapyr can be absorbed through roots and can remain biologically active in soil. That means a tree may be at risk even when its leaves have not been directly sprayed. The same soil activity is why RM43 is a risky choice for clearing a bamboo patch near trees, as our guide on whether RM43 kills bamboo explains.

Important distinction: RM43 is intended for labeled vegetation-control sites, not for indiscriminate application around landscape trees. The label specifically warns against applying it over the root systems of desirable plants.

Which Types of Trees Can RM43 Kill or Damage?

RM43’s registered label lists numerous tree, brush, and vine species that it can control under the specified use conditions. The list includes examples such as alder, ash, aspen, beech, birch, maple, pine, willow, and sweetgum. Some entries are marked for partial control or have additional qualifications.

This list should not be interpreted as a guarantee that every tree of every listed species will die after any exposure. The product label’s target-control information applies to the specified application conditions.

Broadleaf Trees

Broadleaf trees such as maples, ash, and willows may be vulnerable to inappropriate exposure. A university extension response discussing RM43 specifically notes the risk of injury to sugar maples after the product was applied nearby.

Pine and Other Conifers

Pine trees and other conifers should not be assumed to be immune. The RM43 label includes pine among the listed tree and brush species controlled. The degree of injury from unintended exposure still depends on the circumstances.

Conifers can be hurt by other lawn herbicides too, as our guide on whether 2,4-D kills pine trees explains.

Fruit Trees and Ornamental Trees

Fruit trees, flowering trees, and ornamental trees should be protected from off-target exposure. Do not assume that a tree is safe simply because it is not mentioned in a short list of examples.

Root systems may extend into treated areas, and species-specific tolerance is not the same as permission to apply the product near them.

Can RM43 Kill Tree Seedlings and Young Trees?

Young plants may be especially vulnerable to herbicide exposure because they have less established root systems and may have thinner bark. Penn State Extension also warns that accidental glyphosate exposure can cause serious damage to young trees.

The practical rule is simple: do not use RM43 where desirable trees or their roots may be exposed.

What Are the Signs of RM43 Damage to Trees?

Possible symptoms of herbicide injury include:

These symptoms are not unique to RM43. Drought, root damage, disease, pests, nutrient problems, and other chemicals can produce similar signs. A coolant leak near the roots, for example, can also cause yellowing and decline, as our guide on whether antifreeze kills trees explains.

If you suspect accidental exposure, photograph the affected tree, record when and where the product was applied, and keep the product label available for an arborist or qualified plant-health professional.

Can RM43 Damage Nearby Trees Without Direct Spray Contact?

Yes. This is an important distinction between direct spray injury and injury associated with soil-active herbicides.

A tree’s root system may spread well beyond the area directly beneath its branches. Applying RM43 to nearby soil can therefore create a risk even when the spray never touches the tree’s leaves.

Four ways RM43 can reach a nearby tree RM43 can reach a tree through root uptake of imazapyr from treated soil, runoff with surface water, spray drift onto leaves, and shared or grafted roots between neighbouring trees. 4 Ways RM43 Can Reach a Tree No spray marks on the leaves does not prove the tree was never exposed. 1 2 3 4 Root UptakeRunoffSpray DriftShared Roots Roots absorbimazapyr fromtreated soil Product moves withsurface water intoplanted areas Droplets land onleaves, shootsor soft tissue Grafted roots canlink neighbouringtrees Imazapyr can stay active in treated soil, a hidden risk to tree roots.
Four pathways from a treated area to a tree you want to keep.

Potential pathways include:

University extension sources discuss these mechanisms and recommend careful separation between herbicide-treated areas and desirable trees.

This is why the absence of visible spray marks on a tree does not prove that it was never exposed.

RM43 vs. Roundup: Which Is More Powerful?

RM43 and Roundup are not interchangeable products. The comparison depends on which Roundup formulation you mean, because the Roundup brand includes products with different active ingredients and intended uses.

RM43 Total Vegetation Control (glyphosate + imazapyr): Designed for labeled areas where vegetation control and extended prevention of regrowth are desired. The residual activity can create additional risks for nearby desirable plants.

Roundup (formulation varies by product): Many conventional Roundup weed killers use glyphosate to control existing susceptible vegetation. Other Roundup products contain additional active ingredients, so the label matters. The EPA’s glyphosate overview covers how that ingredient is regulated.

The manufacturer confirms that RM43 combines glyphosate with imazapyr, while its residual activity is a key distinction from a glyphosate-only weed killer.

FeatureRM43Glyphosate-only Roundup
Controls existing susceptible weedsYes, when used as labeledYes, when used as labeled
Contains imazapyrYesNo, if it is genuinely glyphosate-only
Can remain active in treated soilYesMuch less root-active residual activity
Risk to nearby treesSignificant if roots or foliage are exposedAccidental exposure can still injure trees
Use around desirable tree rootsThe label warns against itDepends on the exact formulation and label

Which is stronger? RM43 offers a different kind of vegetation control because of its added soil-active ingredient. That does not mean it is universally more effective for every weed, or that it is a better choice for every property.

For tree preservation, the critical issue is avoiding exposure, rather than choosing a product based on which one is described as stronger.

Glyphosate-only Roundup is also slower than many people expect on tough perennial growth, as our guide on whether Roundup kills bamboo explains.

Is RM43 Safer Than Roundup?

RM43 should not automatically be considered safer than Roundup. Safety depends on the exact product, how it is used, the environment, and who or what may be exposed.

The main concern when comparing RM43 with a glyphosate-only formulation is imazapyr’s residual soil activity. It can be taken up by roots and may remain active long after application. Extension guidance warns that imazapyr can injure desirable trees and shrubs when it is used in inappropriate locations.

Glyphosate-only products can also damage desirable plants through accidental spray contact. They are not harmless to trees simply because they generally have less root-active residual activity.

Consider these distinctions:

A product’s ability to prevent regrowth can also become a disadvantage if you later want grass, flowers, shrubs, or trees to grow in that location.

What Is the RM43 Mix Ratio?

The correct RM43 mix ratio depends on the exact product label and the permitted application site. There is no single mix ratio that should be used for every purpose.

For the concentrate, the label gives a general bare-ground vegetation-control rate of 7.4 fluid ounces per 1,000 square feet per year as the maximum annual application rate.

Its directions describe mixing 7.4 fluid ounces with water to make 1 to 10 gallons of spray solution for the specified bare-ground use. The correct amount of water and application method must follow the full label for the intended site.

Label detail (concentrate, bare ground)Figure
Maximum annual rate7.4 fl oz per 1,000 sq ft per year
Spray solution7.4 fl oz mixed with water to make 1 to 10 gallons

A few important points:

If the goal is to preserve a tree, keep RM43 out of its root zone and seek professional advice if the product has already been applied nearby.

What Should You Do If RM43 Gets Near a Tree?

If RM43 has accidentally been applied near a desirable tree, the priority is to prevent further exposure and assess the situation.

  1. Stop further application. Do not spray more product in the area.
  2. Check the label. Identify the exact RM43 formulation and follow its first-aid and spill instructions.
  3. Avoid spreading the product. Do not hose the chemical into other parts of the garden or towards drains and waterways.
  4. Document the exposure. Note the approximate application area, date, amount, soil conditions, and distance from the tree.
  5. Seek qualified advice. Contact an arborist or local agricultural or plant-health extension service. If a substantial spill has occurred, consult the relevant environmental authority.
  6. Monitor the tree. Record changes in foliage, new growth, and canopy condition over time.

Do not automatically excavate roots, apply fertiliser, add other chemicals, or flood the area with water. Those actions may cause additional damage or move the contaminant. A professional can assess whether any intervention is appropriate.

Frequently Asked Questions

Does RM43 kill trees permanently?

It can contribute to severe or fatal tree injury, but the outcome is not guaranteed. Tree survival depends on the species, amount of exposure, application location, soil conditions, and general health. RM43's residual activity is a reason to protect desirable trees from treated soil.

Will RM43 kill a large, mature tree?

A mature tree is not necessarily immune to herbicide injury. Its larger root system may extend into a treated area, and the effects can be delayed. However, you cannot reliably predict whether a particular tree will die based only on its size.

Will RM43 kill pine trees?

Pine is included among the tree species listed in RM43's registered vegetation-control information. That does not establish a guaranteed outcome for every pine tree or every exposure scenario.

Can RM43 kill tree roots?

RM43 can injure susceptible roots when they are exposed to the product, particularly because it contains the soil-active herbicide imazapyr. Avoid applying it over the root systems of desirable trees.

Does RM43 kill weeds forever?

No. The product is marketed for weed control and prevention for up to one year under specified conditions, but this is not a guarantee of permanent bare ground. Rainfall, soil conditions, application quality, and new vegetation entering the area can affect results.

Is RM43 the same as Roundup?

No. RM43 contains glyphosate and imazapyr. Roundup is a brand with multiple formulations, so you need to compare the active ingredients on the specific labels.

Can I plant a tree where RM43 was used?

Do not assume the soil is ready for planting. RM43's label warns against use before planting lawns, fruits, vegetables, flowers, or other plants because the product can remain active in soil for up to a year. Follow the full label's planting restrictions for the particular product and site.

Final Verdict: Will RM43 Kill Trees?

Yes, RM43 can injure trees and may kill them under some exposure conditions. The combination of glyphosate and soil-active imazapyr makes it particularly important to prevent accidental contact with desirable plants and their roots.

The most important distinction is between controlling weeds in a labeled bare-ground area and applying herbicide near trees you want to keep. RM43 is designed for the former, and its label explicitly warns against application over desirable trees’ root systems.

If you are trying to protect a tree, keep RM43 away from its foliage and root zone. If you need to remove a tree, consult a qualified arborist and check local rules before proceeding.

Always follow the current label supplied with your specific product. This article provides general information, not a diagnosis of a particular tree or permission to apply herbicide outside its labeled uses.